Key points
- CDC has recommendations for pre-exposure prophylaxis for certain people.
- If your patient may have been exposed to rabies, contact your health department immediately for a risk assessment to determine eligibility for post-exposure prophylaxis.
- Rabies post-exposure prophylaxis includes wound washing, human rabies immune globulin, and a four-dose series of vaccines.

Rabies biologics
Rabies can be prevented before and after exposure to rabies virus using rabies biologics including vaccine and immunoglobulins.
CDC has recommendations for people who are eligible for pre-exposure prophylaxis (PrEP).
Thanks to rabies control programs and post-exposure prophylaxis (PEP), human rabies is rare the United States, with less than 10 cases reported annually. However, about 100,000 Americans receive PEP following an exposure each year.
Learn more about biologics for preventing rabies through PrEP and PEP, and about increasing their efficacy and safety.